In Silico Comparative Genome Analysis of Hepatitis B and Hepatitis C Virus

In the present study, comparative genome analysis of Hepatitis B and C is done. The similarity and conservation of sequences were analyzed at the genome level by In silico approaches. The study revealed that both the sequences have identical conservation at the sequence level with each other. Both the genomes contain same numbers of the genes and sizes of the genes are almost similar. Most of the sequence patterns of both strains are identical. Thus, although the viruses possessed different size of the genome and slightly different positions and numbers of repeats, they were containing almost similar information at the genome level. Also, it may be possible that hepatitis C has added some genetic information to its viral genome and it may be evolved from hepatitis B.